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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - Doxapram hydrochloride monohydrate

Doxapram hydrochloride monohydrate

CAS No. 7081-53-0

Doxapram hydrochloride monohydrate( AHR 619 )

Catalog No. M15718 CAS No. 7081-53-0

Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Doxapram hydrochloride monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
  • Description
    Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AHR 619
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    TASK-1| TASK-1/TASK-3 heterodimeric| TASK-3
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    7081-53-0
  • Formula Weight
    432.99
  • Molecular Formula
    C24H33ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 2 mg/mL (4.61 mM); Water: 25 mg/mL (57.73 mM); DMSO: 87 mg/mL (200.93 mM)
  • SMILES
    O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl.[H]O[H]
  • Chemical Name
    2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-, monohydrochloride, monohydrate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yost CS. CNS Drug Rev. 2006 Fall-Winter;12(3-4):236-49.
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